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Mouse survival curves. (A) Rates of spontaneous tumor development in Arf GFP/GFP mice observed for up to 44 weeks after birth, as compared with those arising in animals that received a single sublethal dose of ionizing irradiation at 5 days of age. (B) Rates of lymphoma development in Eμ-Myc transgenic mice contrasted on an Arf+/+ or Arf+/GFP genetic background.
