Table 3.
Sensitivity of combined circulatory disease risk estimates to study exclusion (excess relative risk (ERR)/Sv +95% CI) (all assuming as baseline inclusion of Muirhead et al. [14] and exclusion of McGeoghegan et al. [13] (as per bottom row of Table 2 and contribution to heterogeneity χ2 statistic (+degrees of freedom (df)) (reproduced from Ref. [101]).
| Studies excluded | ERR/Sv (95% CI) | χ2 statistic (df) |
|---|---|---|
| A-bomb [8,9] | 0.11 (0.07, 0.14)## | 8.64 (6) |
| US pepticulcer [150] | 0.08 (0.06, 0.11)## | 2.14 (2) |
| UK ankylosing spondylitis [149] | 0.09 (0.06, 0.11)## | 5.99 (2) |
| Massachusetts TB [65] | 0.10 (0.07, 0.13)## | 15.82 (1) |
| IARC 15 country workers [16] | 0.08 (0.05, 0.11)## | 0.00 (1) |
| UK 3rd NRRW analysis [14] | 0.08 (0.05, 0.11)## | 1.32 (1) |
| German uranium miners [148] | 0.08 (0.06, 0.11)## | 4.67 (1) |
| Chernobyl recovery workers [12] | 0.08 (0.05, 0.11)## | 0.84 (1) |
| Mayak workers [15] | 0.04 (0.01, 0.07)# | 53.73 (2) |
| Three Mile Island [147] | 0.08 (0.05, 0.11)## | 11.62 (2) |
| None (All studies) | 0.08 (0.05, 0.11)## | 104.76 (18) |
#
p-value for heterogeneity p < 0.001.
##
p-value for heterogeneity p < 0.00000001.