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. Author manuscript; available in PMC: 2012 Feb 8.
Published in final edited form as: Biochemistry. 2011 Jan 13;50(5):875–881. doi: 10.1021/bi101717b

Fig. 2.

Fig. 2

Binding curves obtained upon titration of B[a]PDE-damaged fluorescein-labeled DNA duplexes (10 nM) with increasing amounts of Dnmt3a-CD in the presence of AdoHcy (0.1 mM). P represents the fluorescence polarization value. Total monomeric enzyme concentration is presented. Designations are: (●) B−CGC/CGMG, (▲) B+CGC/CGMG, (✩) GCB−C/CGMG, (◆) GCB+C/CGMG.