Table 1. Overall comparison of the expression profiles of chromosomal and plasmid-encoded B. burgdorferi genes in the CNS of steroid-treated and competent (NHP).
| NHP | Total hybridizing elements | Up-regulated in the CNS | Down-regulated in the CNS | Expressed at same levels | Specifically induced in the CNS |
|---|---|---|---|---|---|
| Competent chromosomal | 239 | 99 | 7 | 97 | 36 |
| Competent plasmid | 202 | 58 | 2 | 86 | 56 |
| Steroid-treated chromosomal | 243 | 78 | 10 | 139 | 16 |
| Steroid-treated plasmid | 227 | 36 | 4 | 166 | 21 |
Expression profiles in the CNS are relative to that in the heart tissue of the respective NHPs.