Table 3.

Genotype and allele frequencies among boys and girls

			Boys		Girls
	Frequency %		Frequency %		Frequency %
Gene	Subjects without DD	Subjects with DD	Subjects without DD	Subjects with DD	Subjects without DD	Subjects with DD
COL9A3 rs61734651
CC	79.9	86.4	80.8	93.3	79.0	80.6
CT	19.5	13.6	19.2	6.7	19.8	19.4
TT	0.6	0	0	0	1.2	0
T allele	10.3	6.8	9.6	3.3	11.1	9.7
COL11A2 rs1799907
TT	44.9	36.9	42.9	37.9	46.8	36.1
TA	40.1	43.1	38.6	37.9	41.6	47.2
AA	15.0	20.0	18.6	24.1	11.7	16.7
A allele	35.0	41.5	37.9	43.1	32.5	40.3
IL1A rs1800587
CC	46.7	34.9	44.4	48.1	48.8	25.0
CT	42.1	52.4	40.3	37.0	43.8	63.9
TT	11.2	12.7	15.3	14.8	7.5	11.1a
T allele	32.2	38.9	35.4	33.3	29.4	43.1
IL1B rs1143634
CC	52.9	47.0	56.9	50.0	49.4	44.4
CT	34.6	43.9	27.8	46.7	40.7	41.7
TT	12.4	9.1	15.3	3.3	9.9	13.9
T allele	29.7	31.1	29.2	26.7	30.2	34.7
IL6 rs1800797
AA	24.8	23.1	23.3	13.8	30.0	16.7
GA	51.0	50.8	57.5	55.2	45.0	47.2
GG	24.2	26.1	19.2	31.0	25.0	36.1
G allele	49.7	51.5	47.9	58.6	47.5	59.7
IL6 rs1800796
GG	91.5	83.1	86.3	89.7	96.2	77.8
GC	7.9	15.4	12.3	10.3	3.8	19.4
CC	0.7	1.5	1.4	0	0	2.8b
C allele	4.6	9.2	7.5	5.2	1.9	12.5
IL6 rs1800795
CC	24.8	21.2	19.2	26.7	30.0	16.7
GC	51.0	50.0	57.5	53.3	45.0	47.2
GG	24.2	28.8	23.3	20.0	25.0	36.1
G allele	49.7	53.8	52.1	46.7	47.5	59.7
IL6 rs13306435
TT	97.4	98.5	98.6	100	96.3	97.2
TA	2.6	1.5	1.4	0.0	3.7	2.8
A allele	1.3	0.8	0.7	0	1.8	1.4
IL6 rs2069849
CC	92.8	95.5	94.4	96.7	91.4	94.4
CT	7.2	4.5	5.6	3.3	8.6	5.6
T allele	3.6	2.3	2.8	1.7	4.3	2.8
VDR rs2228570
CC	29.1	44.6	25.4	41.4	32.4	47.2
CT	58.9	40.0	58.2	48.3	59.5	33.3
TT	12.1	15.4	16.4	10.3	8.1	19.4
T allele	41.5	35.4	45.5	34.5	37.8	36.1
VDR rs731236
TT	37.0	43.8	39.7	37.9	34.6	48.6
TC	48.0	42.2	49.3	48.3	46.9	37.1
CC	14.9	14.91	11.0	13.8	18.5	14.3
C allele	39.0	35.2	35.6	37.9	42.0	32.9

^adominant model CT/TT vs CC: OR = 2.85 [1.19 - 6.83], p_corr=0.028

^blog-additive model: OR = 6.71 [1.71 - 26.3], p_corr=0.0105