Table 2.
Association of rs1799884 genotype with overall prostate cancer risk
| Number (%) of subjects | ||||||
|---|---|---|---|---|---|---|
| Genotype | Cases (n=1551) | All controls (n = 2993) | OR (95% CI)a | p valuea | ||
| GG | 1,035 | (66.7) | 2,044 | (68.3) | Referent | - |
| GA | 463 | (29.9) | 862 | (28.8) | 11 (0.96 to 1.28) | 0.18 |
| AA | 53 | (3.4) | 87 | (2.9) | 1.40 (0.95 to 2.07) | 0.09 |
| GA/AA | 516 | (33.3) | 949 | (31.7) | 1.13 (0.98 to 1.30) | 0.09 |
| Per allele | - | - | - | - | 1.12 (0.99 to 1.27) | 0.06 |
a
Conditional logistic regression to account for stratum matching of cases and controls on 5-year age bands and primary care recruiting centre, further adjusted for exact age and family history of prostate cancer.
OR, odds ratio; CI, confidence interval.