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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: J Orthop Res. 2011 Mar 28;29(9):1367–1374. doi: 10.1002/jor.21370

Figure 4. Anti-TNF therapy fails to relieve compression induced BME.

Figure 4

Representative longitudinal series of caudal vertebrae post-contrast CE-MRI in placebo treated 6X BW WT (A) and anti-TNF treated 6X BW WT (B) mice showing increase in signal intensity through 14 weeks of compression. Quantification of NMCE (C) illustrates the intensity changes associated with compression, means and standard errors (SE) are shown (n=4 tails; 8 vertebrae for each group). Arrows indicate weekly injections of placebo or anti-TNF treatment (* p<0.05 vs. wk 0 for both groups; # p<0.05 vs. wk 0 for anti-TNF).