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. 2011 Mar 28;108(15):6085–6090. doi: 10.1073/pnas.1015328108

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Fig. 5. — PRMT1 knockdown suppresses BAD-mediated cell death. (A and B) HEK293T (A) and C2C12 (B) cells were transfected with control or PRMT1-specific siRNA together with empty or FLAG-BAD expression vectors. Cell viability was measured using the WST-8 assay. Data are represented as relative cell viability compared with cells with control siRNA. Values are means ± SD of three independent experiments (P < ^∗0.05; n.s, not significant). (C) Whole-cell lysates from C2C12 cells transfected with control or PRMT1-specific siRNA together with empty or FLAG-BAD expression vectors were analyzed by immunoblotting as indicated. (D) Proposed working model.