Table 2.
Engraftment | |
Median transplant cell dose × 107/kg (range) | 1.8 (0.17 – 8.59) |
Median days to sustaineda ANC ≥ 500 (range) | 12 (8 – 30) |
Median days to sustainedb platelet count ≥ 20,000 (range) | 22 (10 – 170) |
GVHD | |
Acute, grade I | 3c |
Acute, grade II | 7 |
Acute, grade III | 4 |
Acute, grade IV | 0 |
Chronic, limited | 5c |
Chronic, extensive | 3d |
Causes of death | |
Relapse | 8 |
Infectious causes | 3 CMV pneumonitis |
7 othere | |
GVHD and secondary complications | 8 |
Interstitial pneumonitis | 2 |
Lung cancer | 1f |
Post-transplant EBV-LPD | 4 |
sustained denotes 3 consecutive days;
sustained denotes 3 consecutive days and platelet transfusion independent;
including one patient post-DLI;
including 2 patients post DLI;
other infections: sepsis (no identified organism) – n=2, E Coli sepsis – n=1, disseminated pseudomonas aeruginosa – n=1, disseminated adenovirus – n=1, toxoplasmosis – n=1; fever with no identified organism – n=1;
the patient who died of lung cancer was also found to have relapsed mantle cell lymphoma on a mediastinal lymph node biopsy.