Table 2.
Participant Characteristics: Health Factors
| MS Total Group EDSS ≤6.5 (n=64) |
Mild Disability EDSS <4.0 (n=43) |
Moderate Disability EDSS 4.0–6.5 (n=21) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Characteristic | Mean | SD | Range | Mean | SD | 95% CI | Mean | SD | 95% CI | p |
| Age (years) | 49.3 | 9.8 | 23–77 | 46.6 | 9.2 | 43.5–49.3 | 54.9 | 8.8 | 50.7–58.7 | <0.001 |
| Male (n=23) | 51.0 | 10.7 | 28–77 | 46.0 | 9.1 | 53.8 | 8.1 | |||
| Female (n=41) | 48.2 | 9.4 | 23–69 | 47.5 | 10.0 | 55.5 | 10.3 | |||
| EDSS score | 3.8 | 1.6 | 1.5–6.5 | 2.8 | 0.5 | 2.6–2.9 | 6.1 | 0.74 | 5.5–6.3 | <0.001 |
| Number of comorbidities | 2.9 | 3.0 | 0–7 | 2.7 | 2.2 | 1.7–3.0 | 3.3 | 4.1 | 1.2–3.3 | 0.441 |
| Number of medications | 5.2 | 3.3 | 1–15 | 4.8 | 2.8 | 4.0–5.8 | 6.0 | 4.2 | 3.9–7.8 | |
| Fatigue (FSS) | 5.1 | 1.3 | 1.3–7.0 | 5.2 | 1.2 | 4.8–5.6 | 5.1 | 1.5 | 4.4–5.7 | 0.999 |
| Weight (kg) | 80.1 | 19.5 | 47.2–134.3 | 81.2 | 21.0 | 74.6–88.1 | 77.7 | 16.2 | 69.7–84.4 | 0.518 |
| Male | 83.8 | 20.1 | 56.7–123.6 | 85.5 | 22.4 | 81.5 | 17.6 | |||
| Female | 77.7 | 19.6 | 47.2–134.3 | 79.5 | 21.2 | 73.1 | 14.3 | |||
| Height (m) | 1.67 | 0.10 | 1.42–1.89 | 1.67 | 0.10 | 1.64–1.70 | 1.68 | 0.10 | 1.63–1.72 | 0.524 |
| Male | 1.71 | 0.10 | 1.52–1.88 | 1.75 | 0.09 | 1.69 | 0.10 | |||
| Female | 1.65 | 0.10 | 1.42–1.89 | 1.64 | 0.07 | 1.66 | 0.10 | |||
| BMI (kg/m2) | 28.3 | 6.2 | 18.2–45.0 | 29.0 | 6.7 | 26.8–31.2 | 27.3 | 4.5 | 25.4–29.5 | 0.294 |
| HR (bpm) | 78.2 | 10.4 | 55–108 | 79.0 | 11.4 | 75.3–82.6 | 76.6 | 8.0 | 73.3–80.1 | 0.556 |
| Systolic BP (mm Hg) | 125.8 | 17.7 | 100–178 | 126.1 | 18.7 | 120.9–132.8 | 125.7 | 16.5 | 115.6–130.3 | 0.941 |
| Diastolic BP (mm Hg) | 81.8 | 8.8 | 62–100 | 81.9 | 9.6 | 79.4–85.3 | 80.7 | 6.1 | 76.7–83.5 | 0.599 |
| ABC Score** | 64.4 | 22.5 | 14.4–99.4 | 74.6 | 18.2 | 69.2–81.5 | 45.1 | 16.5 | 38.4–54.1 | <0.001 |
| Male | 63.6 | 21.8 | 14.4–98.1 | 79.2 | 19.3 | 67.5–90.9 | 49.2 | 18.8 | 35.7–62.7 | |
| Female | 66.1 | 24.1 | 15.0–99.4 | 73.3 | 17.3 | 65.7–80.7 | 43.6 | 16.1 | 32.8–54.4 | |
*
One-way ANOVA significant at p<0.05
**
n=64 (except n=58 for ABC scores)
MS=multiple sclerosis; CI=confidence interval; EDSS=Expanded Disability Status Scale; FSS=Fatigue Severity Scale
BMI=body mass index; HR=heart rate; bpm=beats per minute; BP=blood pressure; ABC=Activities-specific Balance Confidence Scale