Table 4.
Health Factors, Physical Performance, and Pulmonary Function Correlated with 6-Minute Walk Test
| Measures Correlated with 6MWT |
Partial* |
R2 |
|---|---|---|
| Health Factors | ||
| EDSS | −0.588*** | 0.346 |
| Number of comorbidities | 0.026 | 0.001 |
| Number of medications | −0.056 | −0.001 |
| Fatigue (FSS) | 0.003 | 0.001 |
| BMI (kg/m2) | −0.065 | 0.004 |
| HR | −0.126 | 0.016 |
| Systolic BP | −0.180 | 0.032 |
| Diastolic BP | −0.200 | 0.040 |
| ABC score) |
0.771*** |
0.594 |
| Physical performance measures |
|
|
| FST | −0.756*** | 0.572 |
| SST | −0.571*** | 0.326 |
| BAL | 0.395*** | 0.156 |
| Pulmonary function measures |
|
|
| MIP observed | 0.281** | 0.079 |
| MIP predicted | 0.314** | 0.099 |
| MEP observed | 0.404*** | 0.163 |
| MEP predicted | 0.302** | 0.091 |
| MVV observed | 0.304** | 0.092 |
| MVV predicted | 0.321*** | 0.103 |
| FEV1 observed | 0.111 | 0.012 |
| FEV1 predicted | 0.113 | 0.013 |
| FVC observed | 0.043 | 0.002 |
| FVC predicted | 0.073 | 0.005 |
| FEV1/FVC | 0.086 | 0.007 |
*
Partial correlation controlling for age
**
p<0.05
***
p<0.01
6MWT=6-Minute Walk Test; EDSS=Expanded Disability Status Scale; BMI= body mass index; FSS=Fatigue Severity Scale; ABC=Activities-specific Balance Scale; FST=Functional Stair Test; SST=Sit-to-Stand Test; BAL=single-limb or tandem balance; HR=heart rate; BP=blood pressure; MIP=maximal inspiratory pressure; MEP=maximal expiratory pressure; MVV=maximal voluntary ventilation; FEV1=forced expiratory volume in 1 second; FVC=forced vital capacity; FEV1/FVC=forced expiratory volume in 1 second / forced vital capacity