Table 2.

Fraction of hepatic glycolytic flux supported by plasma glucose measured as the ratio of [3-¹³C]lactate and [3-¹³C]alanine to plasma [1-¹³C]glucose from low-fat and high-fat fed animals during fasting, hyperinsulinemic euglycemic clamp with and without a concomitant liposyn infusion and hyperinsulinemic hyperglycemic clamp

		Fasting	Hyperinsulinemic Euglycemic Clamp	Hyperinsulinemic Hyperglycemic Clamp	Hyperinsulinemic Euglycemic Clamp + Liposyn
Low Fat Diet	[1-13C]Alanine	10.2±1.3%	18.4±0.9%	31.1±3.4%**†	11.3±1.6%¥
	[1-13C]Lactate	12.8±1.1%	20.5±1.0%	31.3±4.1%**†	13.1±1.7%¥
High Fat Diet	[1-13C]Alanine	14.6±2.1%	6.3±2.3%‡	23.8±1.5%*†
	[1-13C]Lactate	12.8±2.8%	7.0±1.6%‡	24.6±0.8%*†

^*P<0.05,

^**P<0.0001 compared to Fasting

^†P<0.0001 compared to Hyperinsulinemic Euglycemic Clamp

^¥P<0.0001 compared to Hyperinsulinemic Hyperglycemic Clamp

^‡P<0.05 compared to the same group from the low-fat fed animals