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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Mol Cancer Res. 2011 Mar 1;9(3):259–270. doi: 10.1158/1541-7786.MCR-10-0469

Figure 2.

Figure 2

Radiation induces delayed HIF-1 signaling in A) #4C6 and B) HN5 xenografts. Top: whole animal 18F-FEAU PET imaging, with tumors indicated by ovals. Bottom left: pooled quantification of 18F-FEAU tumor-muscle signal ratio (TMR; *, p < 0.05 between treatment groups; **, p < 0.005 between treatment groups). Bottom right: volumetric tumor growth over time, reported as mean tumor volume values +/− standard error; ***, p < 0.001.