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. Author manuscript; available in PMC: 2011 Apr 14.
Published in final edited form as: Vasc Med. 2010 Apr 7;15(3):215–222. doi: 10.1177/1358863X10362831

Table 4.

Effect of weight loss on metabolic parameters and brachial artery characteristics

Modest weight loss n = 27
Significant weight loss n = 40
Baseline 1 year Baseline 1 year
BMI, kg/m2 45 ± 9 43 ± 9a 48 ± 9 34 ± 7a
Weight, kg 127 ± 29 122 ± 29a 131 ± 24 94 ± 17a
Systolic blood pressure, mmHg 132 ± 18 127 ± 18 131 ± 14 130 ± 14
Diastolic blood pressure, mmHg 74 ± 13 74 ± 12 72 ± 11 74 ± 11
Total cholesterol, mg/dl 182 ± 28 181 ± 28 192 ± 34 182 ± 33
HDL cholesterol, mg/dl 46 ± 11 48 ± 11 52 ± 19 53 ± 14
LDL cholesterol, mg/dl 102 ± 30 107 ± 28 108 ± 28 106 ± 27
Triglycerides, mg/dl 158 ± 124 136 ± 86 161 ± 100 120 ± 70b
Glucose, mg/dl 104 ± 36 104 ± 29 114 ± 43 99 ± 45b
Insulin, μIU/ml 13.4 ± 10.1 13.5 ± 10.0 20.3 ± 16.9 7.5 ± 6.1a
hsCRP, mg/l 13.6 ± 5.2 11.5 ± 5.2b 10.3 ± 6.6 5.0 ± 5.5a
Baseline diameter, mm 4.11 ± 0.86 4.19 ± 0.79 4.21 ± 0.71 4.02 ± 0.66c
Post-nitroglycerin diameter, mm 4.76 ± 0.86 4.84 ± 0.92 5.14 ± 0.62 4.78 ± 0.60d
Baseline flow velocity, cm/sec 19 ± 8 22 ± 9 21 ± 7 23 ± 12
Baseline flow, ml/min 166 ± 116 190 ± 117 174 ± 65 167 ± 81
Baseline shear stress, dyne/cm2 13.5 ± 6.7 14.9 ± 6.2 14.4 ± 6.0 16.7 ± 11.1e

Mean ± SD.

a

p < 0.001,

b

p < 0.05,

c

p = 0.01,

d

p < 0.01,

e

p = 0.08 compared to baseline. hsCRP; high-sensitivity C-reactive protein.