. 2010 Nov 25;2(1):36–50.

Table 5.

Genotype distributions of the polymorphisms in CTNNBL1 in the hospital-based Czech and the family/early onset-based German sample population showing combined results adjusted for age, gender and nationality

SNP	Allele^a	Sample	Genotype distribution^b		Codominat Model						Dominant Model
			DD-DA-AA		DD vs DA			DD vs AA			DD vs DA+AA
			Cases	Controls	OR	95% CI	P	OR	95%	CI	P	OR	95%
		Czech	606-111-2	658-80-3	1.47	1.07-2.02	0.02	0.82	0.13-5.29	0.84	1.45	1.06-1.98	0.02
rs2344481	A/G	German	561-81-4	554-69-4	1.16	0.82-1.63	0.40	0.95	0.23-3.83	0.94	1.15	0.82-1.61	0.42
		Czech & German	1167-192-6	1212-149-7	1.34	1.06-1.68	0.01	0.99	0.33-2.98	0.98	1.32	1.05-1.66	0.02

		Czech	42-234-445	27-237-478	0.60	0.35-1.03	0.06	0.57	0.34-0.95	0.03	0.58	0.35-0.97	0.04
rs2281148	C/T	German	37-199-418	41-212-408	1.08	0.66-1.76	0.76	1.15	0.72-1.83	0.57	1.12	0.71-1.77	0.64
		Czech & German	79-433-863	68-449-886	0.81	0.56-1.15	0.23	0.83	0.59-1.16	0.27	0.82	0.59-1.15	0.25

		Czech	96-342-262	124-368-243	1.20	0.89-1.65	0.26	1.39	1.00-1.93	0.05	1.28	0.95-1.72	0.11
rs2235460	A/G	German	97-302-207	120-311-214	1.21	0.88-1.65	0.24	1.19	0.86-1.66	0.30	1.20	0.89-1.61	0.22
		Czech & German	193-644-469	244-679-457	1.21	0.97-1.51	0.09	1.31	1.04-1.65	0.02	1.25	1.01-1.54	0.04

OR odds ratio; CI confidence interval; A ancestral allele, D derived allele.

Second allele represents the ancestral allele for each locus.

Total numbers of cases and controls may slightly vary among SNPs due to missing genotypes. Bold numbers indicate statistical significance at 5% level. The results were adjusted for age due to significant difference in the median age distribution among the case and the control group.