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Hippocampal CA1 dendritic spine density following DMI treatment. (a, b) Representative photomicrographs of Golgi impregnation staining to visualize dendritic arborization following saline (a) or DMI (b) treatment in AAV.eGFP-injected mice. (c) Chronic DMI treatment significantly increased CA1 dendritic spine density in AAV.eGFP-injected mice (***p<0.001, n=30–42 per group). This effect was attenuated in AAV.Cre-injected mice. (*p<0.05). Error bars indicate SEM.
