Table 4. Clinical data during liver transplantation in patients receiving a IP and non-IP allograft.
Non-steatotic allografts |
Steatosic allografts |
|||||||
---|---|---|---|---|---|---|---|---|
Variable | IP (n=14) group I | Non-IP (n=14) group II | IP (n=12) group III | Non-IP (n=10) group IV | P-value I versus IIa | P-value III versus IVa | P-value I versus IIIa | P-value II versus IVa |
Hepatic function | ||||||||
AST at day 5 (IU/l) | 42±33 | 79±57 | 55±40 | 139±164 | 0.047 | 0.10 | 0.37 | 0.22 |
ALT at day 5 (IU/l) | 82±39 | 247±194 | 222±246 | 423±409 | 0.005 | 0.17 | 0.046 | 0.17 |
AST peak (IU/l) | 235±189 | 458±308 | 881±1323 | 862±762 | 0.029 | 0.96 | 0.08 | 0.09 |
ALT peak (IU/l) | 187±94 | 577±361 | 795±796 | 728±724 | 0.0006 | 0.84 | 0.009 | 0.51 |
PT (%) at day 5 | 61±13 | 67±10 | 63±20 | 68±9 | 0.18 | 0.48 | 0.73 | 0.74 |
Bilirubin at day 7 (μmol/l) | 46±44 | 38±21 | 106±148 | 78±45 | 0.55 | 0.57 | 0.16 | 0.007 |
Hospitalization | ||||||||
Intensive care unit stay (days) | 12±7 | 11±6 | 15±10 | 12±5 | 0.67 | 0.42 | 0.47 | 0.59 |
Total stay in hospital (days) | 28±8 | 29±13 | 52±43 | 33±9 | 0.70 | 0.18 | 0.049 | 0.53 |
Retransplantation | 1/14 | 1/14 | 0/12 | 0/10 | — | — | 0.52 | 0.52 |
Rejection | ||||||||
Acute rejection | 2/14 | 5/14 | 2/12 | 6/10 | 0.15 | 0.048 | 0.40 | 0.17 |
Rejection activity index (mean±S.D.) | 5±1.4 | 5.2±1.3 | 5±1.7 | 4.7±0.9 | 0.86 | 0.73 | 1.00 | 0.66 |
Acute rejection delay (median in month) | 0.5 | 1.25 | 0.5 | 2 | 0.84 | 0.92 | 0.99 | 0.99 |
Chronic rejection | 0/14 | 2/14 | 2/12 | 7/10 | 0.24 | 0.017 | 0.20 | 0.009 |
Ductopenia (mean±S.D. in %) | — | 44.5±15.6 | 49.7±23.1 | 36.5±10.2 | — | 0.15 | — | 0.22 |
Chronic rejection delay (median in month) | — | 42 | 9 | 36 | — | 0.09 | — | 1.00 |
Follow-up (mean±S.D. in months) | 53±18 | 60±30 | 47±27 | 64±26 | 0.44 | 0.16 | 0.51 | 0.76 |
Means were compared using the Student's t-test
Dichotomous variables were compared using the Fisher exact test
Medians were compared with Kolmogorov–Smirnov test