Figure 4.

Ion channel inhibitors partially reduced cyt c release. (a) The presence of cyt c in the cytosol was detected by western blot assay. The optical density ratio (cyt c/β-tubulin) was normalized considering the effect of STS as 100%. (b) FA did not have any effect on STS-induced cyt c release, but the combination of K⁺ channel inhibitors (T+4) reduced significantly the STS-induced cyt c release, while the addition of FA did not increase any further the inhibitory effect of the combination of K⁺ channel inhibitors (n=15). ^*P<0.05