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. Author manuscript; available in PMC: 2011 Sep 10.
Published in final edited form as: Neuroscience. 2010 Dec 31;176:72–85. doi: 10.1016/j.neuroscience.2010.12.041

Figure 3. BDNF-dependent internalization of surface GABAARα1 subunits is attenuated by K252a treatment in hippocampal neurons.

Figure 3

Panel A illustrates light microscopic images of surface (green) GABAARα1 subunits following vehicle, BDNF, or BDNF + k252a treatment for 5, 10, or 20 minutes. Panel B demonstrates quantification of fluorescence intensity of surface alpha 1, normalized with controls. Panel C illustrates images of internalized (red) GABAARα1 subunits following vehicle, BDNF, or BDNF + k252a treatment for 5, 10, or 20 minutes. Panel D demonstrates quantification of fluorescence intensity of internalized α1, normalized with controls. (Mean ± SEM of normalized intensity, * p <0.001, ** p<0.05, relative to no treatment).