Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2011 Apr 1;4:8. doi: 10.1186/1755-8166-4-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2011 Rocha et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Metaphase and interphase FISH. (a) FISH showing 3 signals for CCND1 due to a translocation at the CCND1 locus on 11(q13). CCND1 on 11(q13) is marked in red, IGH on 14(q32) is marked in green. (b) FISH confirming IGL rearrangement with an IGL dual-color breakapart probe. Broad arrows show separated signals for the IGL proximal region in red and for the distal region in green. The open arrow shows a fusion signal for the normal chromosome 22. (c) FISH with a CCND1/IGL tri-color, dual-fusion probe, showing the IGL/CCND1 translocation. CCND1 on 11(q13) marked in Spectrum Orange and Spectrum Green, IGL on 22(q11.2) marked in Spectrum Aqua. The broad arrow shows the derivative chromosome 22 and the open arrow the derivative chromosome 11.