Table 1.
BLAST homology searches using apoptosis DNases as queries
| Name Species ID | CAD | ICAD | EndoG | ZEN1 | NUC1 |
|---|---|---|---|---|---|
| D. melanogaster Q9NDR2 | H. sapiens DFFA_HUMAN | H. sapiens NUCG_HUMAN | H. vulgare O81958 | C. elegans NUC1_CAEEL | |
| D. melanogaster | Q9NDR2 1.5e-236 | Q6NR36 0.051 | Q7JXB9 1.4e-61 | No | Q7JYM9 3.2e-46 |
| H. sapiens | O76075 5.3e-22 | DFFA_HUMAN 2.1e-161 | NUGG_HUMAN 1.5e-129 | No | A0AUY7 1.5e-46 |
| C. elegans | No | No | NUCG_CAEEL 9.2e-56 | No | NUC1_CAEEL 1.0e-198 |
| S. cerevisiae | No | No | NUC1_YEAST 6.1e-43 | No | No |
| T. brucei | No | No | Q581C4 8.2e-20 | Q585P6 1.2e-06 | No |
| L. major | No | No | Q4QHF4 1.4e-19 | Q4QGQ3 1.3e-06 | No |
| T. gondii | No | No | B9PXN1 3.7e-23 | B6KFB6 0.087 | No |
| P. falciparum | No | No | No | C0H524 9.9e-05 | No |
| T. thermophila | No | No | No | Q236I5 0.00016 | Q22N03 2.1e-35 |
| Plants | No | No | B9P690 (P. trichocarpa) 0.00034 | O81958 (H. vulgare) 3.7e-146 | No |
| T. vaginalis | No | No | No | A2E6R1 2.9e-06 | A2F6V7 2.2e-41 |
Sequences of five different DNases were used as queries to search the UniProt databases (wublast using EBI www server) [47]. Each query DNase represents a different column and homologues detected in other organisms are presented in each row. The UniProt IDs for query and detected sequences are given and the expected values presented below each ID.