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. 2011 Apr 14;6(4):e18564. doi: 10.1371/journal.pone.0018564

Figure 3. Theinhibition of MHC class II and CD64 by Rvexosomesis dependent on macrophage expression of TLR2.

Figure 3

Untreated or exosome-treated BMMØ isolated from TLR2-deficient mice were stimulated +/− IFN-γ. Macrophages were harvested, stained with PE-conjugated anti-MHC class II or anti-CD64 antibody and analyzed by flow cytometry. Shown are the mean fluorescence intensity values for MHC-II (A) and CD64 (B) expression. Results are representative of two independent experiments plus standard deviation and p value <0.05 between +/− IFN-γ treatments are indicated by asterisk (*).