Table 3. Association between DHEAS-associated SNPs and related gene expression levels in different human tissues.

Gene	Chr	SNP (effect allele)	Position	LCL* (n = 777)		Adipose tissue* (n = 776)		Skin tissue* (n = 667)		Liver tissue¶ (n = 427)
				Beta (SE)	P value	Beta (SE)	P value	Beta (SE)	P value	P value
BCL2L11	2	rs6738028 (G)	111665798	0.07 (0.02)	0.0003	0.02 (0.005)	0.001	−0.00004 (0.005)	0.99	Not available
TRIM4	7	rs17277546 (A)	99327507	0.15 (0.04)	0.0001	0.13(0.04)	0.002	0.10(0.04)	0.01	Not available
SULT2A1	19	rs2637125 (A)/rs2547231**	53093705	0.0006 (0.007)	0.93	−0.009(0.007)	0.19	0.02(0.007)	0.01	2.16×10−11

*from MuTHER consortium and beta (SE) were from linear regression modelling; LCL – lymphoblastoid cell lines.

¶: from reference 27 and effect size was not reported.

**p value in liver expression is for rs2547231, data is not available for rs2637125, but two SNPs are in strong LD (r² = 0.658).