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. 2011 Apr 14;6(4):e18628. doi: 10.1371/journal.pone.0018628

Figure 4. Reduced small intestinal and colonic contractility in the smDicer knockout mutants compared to the wild type controls.

Figure 4

(A–D) The effects of ACh (1 & 10 µM) on the small intestines and colons of control (A, C) and mutant tissues (B, D) respectively (solid bars indicate the time of exposure). (E–H) The effect of increasing extracellular [K+] (48 & 96 mM) in small intestines and colons of control (E, G) and mutant tissues (F, H). Experiments were preformed in the presence of L-NNA (100 µM) to reduce influences from inhibitory motor nerves. (n = 3)