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. 2011 Apr 14;6(4):e18642. doi: 10.1371/journal.pone.0018642

Table 3. Association of HRM score and survival in univariate (unadjusted) models and multivariate (adjusted) models that included HRM score and HIV viral load.

HRM score at 6–8 weeks N Hazard Ratio (95% CI) Unadjusted P N Hazard Ratio (95% CI) Adjusted 1 P
Gag1 31 2.0 (0.7, 6.0) 0.19 26 2.1 (0.7, 6.6) 2 0.19
2.6 (0.8, 9.2) 3 0.12
Gag2 31 2.5 (0.8, 7.3) 0.11 26 3.5 (1.1, 10.9) 2 0.03
2.4 (0.7, 7.8) 3 0.15
Pol 30 4.7 (1.4, 15.8) 0.01 25 3.4 (1.0, 11.9) 2 0.06
2.7 (0.7, 10.6) 3 0.15
Mean (Gag1, Gag2) 31 4.2 (1.5, 11.9) 0.006 26 8.7 (2.6, 28.6) 2 0.0004
3.4 (1.1, 10.8) 3 0.04
Mean (Gag1, Gag2, Pol) 30 4.6 (1.6, 13.2) 0.004 26 6.9 (2.1, 22.9) 2 0.002
1.7 (0.5, 5.3) 3 0.40
1

Two covariates were included in each multivariate model: HRM score measured at 6–8 weeks of age (binary, ≤75th percentile vs. >75th percentile) and HIV viral load measured at 14 weeks of age (log10 scale). N: number of infants included in the model; CI: confidence intervals

2

Hazard ratio, 95% CI, and P value for HRM score at 6–8 weeks of age.

3

Hazard ratio, 95% CI, and P value for HIV viral load at 14 weeks of age (log10 scale).