Table 3. Association of HRM score and survival in univariate (unadjusted) models and multivariate (adjusted) models that included HRM score and HIV viral load.
HRM score at 6–8 weeks | N | Hazard Ratio (95% CI) Unadjusted | P | N | Hazard Ratio (95% CI) Adjusted 1 | P |
Gag1 | 31 | 2.0 (0.7, 6.0) | 0.19 | 26 | 2.1 (0.7, 6.6) 2 | 0.19 |
2.6 (0.8, 9.2) 3 | 0.12 | |||||
Gag2 | 31 | 2.5 (0.8, 7.3) | 0.11 | 26 | 3.5 (1.1, 10.9) 2 | 0.03 |
2.4 (0.7, 7.8) 3 | 0.15 | |||||
Pol | 30 | 4.7 (1.4, 15.8) | 0.01 | 25 | 3.4 (1.0, 11.9) 2 | 0.06 |
2.7 (0.7, 10.6) 3 | 0.15 | |||||
Mean (Gag1, Gag2) | 31 | 4.2 (1.5, 11.9) | 0.006 | 26 | 8.7 (2.6, 28.6) 2 | 0.0004 |
3.4 (1.1, 10.8) 3 | 0.04 | |||||
Mean (Gag1, Gag2, Pol) | 30 | 4.6 (1.6, 13.2) | 0.004 | 26 | 6.9 (2.1, 22.9) 2 | 0.002 |
1.7 (0.5, 5.3) 3 | 0.40 |
Two covariates were included in each multivariate model: HRM score measured at 6–8 weeks of age (binary, ≤75th percentile vs. >75th percentile) and HIV viral load measured at 14 weeks of age (log10 scale). N: number of infants included in the model; CI: confidence intervals
Hazard ratio, 95% CI, and P value for HRM score at 6–8 weeks of age.
Hazard ratio, 95% CI, and P value for HIV viral load at 14 weeks of age (log10 scale).