Table 2. Somatic aneuploidy in human skeletal muscle from MD patients.
disomies (%) | aneusomies (%) | |||||||
Group | Sample ID | Age (a) | chr2 | chr13 | chr19 | chr2 | chr13 | chr19 |
Controls | ||||||||
Control-fetal | FK | prenatal | 88 | 91 | 85 | 0.0 | 0.0 | 1.0 |
Control-fetal | FP | prenatal | 91 | 94 | 88 | 0.5 | 0.0 | 1.4 |
Control | M2232 | 2 | 87 | 81 | 79 | 0.7 | 1.0 | 1.3 |
Control | M1856 | 3 | 87 | 67 | 81 | 0.8 | 2.1 | 1.1 |
Control | M2066 | 4 | 91 | 93 | 84 | 1.1 | 0.0 | 0.7 |
Control -adult | M826 | 44 | 93 | 87 | 79 | 0.5 | 0.5 | 0.5 |
Control -adult | M1006 | 49 | 87 | 79 | 70 | 1.1 | 1.4 | 0.0 |
Control -adult | M983 | 52 | 87 | 91 | 70 | 2.3 | 0.0 | 1.1 |
Control -adult | M689 | 52 | 84 | 74 | 77 | 1.1 | 1.6 | 1.7 |
DMD | ||||||||
DMD-fetal | FL | prenatal | 85 | 93 | 86 | 2.2 | 0.6 | 4.9 |
DMD-fetal | FB | prenatal | 83 | 92 | 81 | 0.0 | 0.5 | 1.4 |
DMD | M2006 | 1 | 82 | 88 | 84 | 2.7 | 0.0 | 3.3 |
DMD | M1994 | 7 | 71 | 82 | 70 | 8.3 | 2.4 | 6.8 |
DMD | M1895 | 8 | 76 | 86 | 66 | 5.9 | 3.6 | 8.8 |
DMD | M1959 | 15 | 58 | 75 | 54 | 11.2 | 2.0 | 6.1 |
DYSF | ||||||||
LGMD2B-adult | M2057 | 62 | 58 | n.a. | 46 | 17.7 | n.a. | 7.5 |
FKRP | ||||||||
MDC1C-fetal | M2166 | prenatal | 88 | 89 | 83 | 1.7 | 0.5 | 2.6 |
LGMD2I | M1787 | 10 | 69 | 81 | 55 | 7.3 | 1.9 | 6.1 |
LGMD2I -adult | M2190 | 28 | 62 | 80 | 62 | 7.1 | 0.7 | 3.3 |
CAPN3 | ||||||||
LGMD2A | M1883 | 9 | 77 | 84 | 66 | 3.9 | 4.1 | 4.6 |
LGMD2A | M2207 | 13 | 79 | 87 | 77 | 6.1 | 6.0 | 4.6 |
LGMD2A-adult | M2219 | 25 | 73 | 84 | 70 | 3.8 | 3.5 | 2.8 |
n.a.: not analyzed