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. 2010 Sep 20;21(5):1094–1104. doi: 10.1093/cercor/bhq181

Figure 2.

Figure 2.

Similar direct excitation profiles of layer V pyramidal (Pyr) neurons and FS interneurons in control and undercut neocortex. (A) Average AP maps in Pyr neurons. Areas of 400 × 400 μm were photostimulated by laser flashes with a 50 μm spacing and the mean number of APs evoked by each spot plotted in control (Ctr, left) and undercut neurons (UC, right). Most of the APs were activated by stimuli close to the somata of the recorded neurons. Black triangle: somata of pyr neurons. (B andC) Analysis of direct excitation profiles in Pyr neurons. There were no significant differences between the control (n = 20) and undercut (n = 20) in average number of hotspots (B) and evoked APs (C) relative to different distances to somata. (D) Average AP maps in FS interneurons. The intensity and size of the average maps were similar between the control and undercut neurons. Black circle: somata of FS cells. (E andF) Analysis of direct excitation profiles in FS cells. There were no significant differences between the control (n = 14) and undercut (n = 18) in number of hotspots (E) and evoked APs (F) relative to distances to somata. Note that most APs were generated within a region 150 μm from somata in all average maps. Scale bar in (A) and (D): 50 μm. Scale to right in (A) and (D): mean number of APs evoked by spots. White bar: control group; black bar: undercut group.