. Author manuscript; available in PMC: 2012 Apr 1.

Published in final edited form as: J Cardiovasc Pharmacol. 2011 Apr;57(4):376–379. doi: 10.1097/FJC.0b013e3182116e39

Table 1.

Various Elements Secreted by Myofibroblasts

Chemokines	IL-1α and β, IL-6, IL-10, TNF-α
Cytokines	ENA-78, GRO-1α, IL-8. MCP-1, MIP-1α, MIP-2, RANTES
Growth Factors	CSF-1, bFGF, GM-CSF, HGF, IGF-I, IGF-II, KGF, NGF, PDGF-AA, PDGF-BB, SCF, TGF-β
Inflammatory Mediators	CO, H₂O₂, HETEs, NO, O⁻, PAF, PGE₂, Phospholipase A₂ activating protein, Prostacyclin

bFGF= Basic fibroblast growth factor, CSF= Colony-stimulating factor, ENA= Epithelial neutrophil-activating peptide, GM-CSF= Granulocyte/macrophage colony-stimulating factor, GRO= Melanoma growth-stimulatory activity, HETEs= Hydroxyeicosatetraenoic acids, HGF= Hepatocyte growth factor, IGF= Insulin like growth factor, IL=Interleukin KGF=Keratinocyte growth factor, MCP= Monocyte chemoattractant protein, MIP=Macrophage protein, NGF= Nerve growth factor, PAF= Platelet activating factor PDGF= Platelet-derived growth factor, RANTES= Regulated upon activation, normal T cell expressed and secreted, SCF= Stem cell factor, TNFα = Tumor necrosis factor alpha, TGFβ=Transforming growth factor beta, VEGF= Vascular endothelial growth factor