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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Glia. 2011 Mar 24;59(6):997–1007. doi: 10.1002/glia.21171

Fig. 2.

Fig. 2

gp120 enhances microglia whole-cell outward K+ current in a dose-dependent manner. A. Typical outward K+ currents recorded from a control and a gp120-treated microglia as indicated. B. I-V curves showing gp120 increases outward K+ current. C. gp120 increases outward K+ current in a dose-dependent manner. The graph plots mean outward K+ current densities measured at +60 mV. D. Outward K+ current recorded in microglia before (Ctrl), during (gp120) and after (wash) bath application of gp120 (200pM). E. Average outward K+ current densities recorded in microglia cells as shown in D (n=5) and in another 5 microglia treated with heat (boiled)-inactivated gp120, illustrating gp120 specific enhancement of outward K+ current. *, p<0.05 vs Ctrl; **, p<0.01 vs Ctrl; #, p<0.05 vs boiled gp120.