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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: Q J Nucl Med Mol Imaging. 2010 Jun;54(3):291–308.

Figure 4.

Figure 4

Dual-labeled integrin-binding knottin peptide for microPET and NIRF imaging. A. MicroPET imaging of DOTA/Cy5.5-knottin peptide in mice bearing U87MG tumor. B. Mice were co-injected with an excess amount of unlabeled c(RGDyK) in addition to labeled knottin peptides as blocking experiment. C. NIRF imaging of DOTA/Cy5.5-knottin peptide in mice bearing U87MG tumor (arrows indicate U87MG tumors). D. Mice were co-injected with an excess amount of unlabeled c(RGDyK) in addition to labeled knottin peptides as blocking experiment. T, tumor; K, kidney; Bd, bladder; L, liver. Reproduced from reference 134 with permission.