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Body weights of 7-day-old Kir4.1+/+, Kir4.1+/−, and Kir4.1−/− pups
The body weights of Kir4.1−/− mice on day 7 were significantly reduced compared with their Kir4.1+/+ and Kir4.1+/− littermates (p < 0.001). Null mutants exhibited little growth beyond that age, with few exceeding 4 g.
| Genotype | Weight |
|---|---|
| g | |
| Kir4.1+/+ (n = 23) | 4.88 ± 0.17 |
| Kir4.1+/− (n = 17) | 4.87 ± 0.19 |
| Kir4.1−/− (n = 19) | 3.46 ± 0.08 |
