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Mass spectra of GES-2 inactivated by tazobactam. The mass spectra of the deconvoluted LC/MS after electrospray ionization of native GES-2 (A) and the GES-2/tazobactam intermediates formed immediately after the initiation of inactivation (B) and after 20 min of inactivation (c) are shown. The arrow indicates the position of the native GES-2 enzyme and all mass changes are relative to this peak.
