FIGURE 6.

Caspase-truncated RET increases N-cadherin aggregative properties. L cells were co-transfected with N-cadherin plasmid (1/5 of total cDNA) and vector or different RET constructs (4/5 of total cDNA). After 48 h of transfection, expression of N-cadherin and RET constructs was analyzed by Western blotting (WB; lower left panels), and in parallel, aggregation assays were performed. Upper panels are representative dark field microscopy images. Scale bars, 50 μm. Lower right panel, quantification corresponds to the average of three independent experiments. **, p < 0.01 analyzed by Student's test.