Figure 5.
Illustrations of cell movement represented by rules in the cell module. The tip cell is represented by a red node and segment; the node shared between the tip and stalk cells is yellow; and the blue node and segment is the adjacent stalk cell segment. Black segments and nodes represent quiescent vessels. Arrows represent direction of movement for nodes. (A) Schematic of a capillary with an activated tip cell. (B) Movement and the resulting cell segment positions when there is a VEGF gradient, showing the effects of allowed elongation and tip cell proliferation.