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. Author manuscript; available in PMC: 2011 Apr 15.
Published in final edited form as: Dev Biol. 2009 Jul 14;334(1):46–58. doi: 10.1016/j.ydbio.2009.07.007

Figure 2. Dynamics of blastomere contact during the 2-cell stage.

Figure 2

(A) Schematic depicting the measurements taken from images of live embryos (see Fig. 1B) at time points shown in (B) and (C). The maximum width of CD perpendicular to the AB-CD axis (tri-colored bar) is defined as 100%. (B) Graphical representation of the changes in width and relative position of the interface, averaged from 3-5 embryos per time point; error bars for the overhangs are shown in (C). (C) Systematic loss of bilateral symmetry midway through the 2-cell stage is revealed by comparing the average and standard deviation of the left (black bars) and right (gray bars) overhangs. The left and right sides of the embryo differ significantly (*) starting at 375′ (p≤0.01, students t-test).