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Sensitivity to change analysis of SLEDAI-2000 index with minimal increase in score of 3 to indicate worsening and minimal decrease in score of 1 to indicate improvement (n = 1414)
| Change in SLEDAI-2000 score | Number of observations | Increase in therapy OR (95% CI) | Decrease in therapy OR (95% CI) |
|---|---|---|---|
| Minimal change | 863 | 1.00 | 1.00 |
| Increase ≥3 | 142 | 10.57 (6.20, 18.01) | 1.89 (1.03, 3.47) |
| Decrease ≥1 | 409 | 1.05 (0.74, 1.49) | 1.97 (1.51, 2.56) |
