Table 1.

Comparison of the sensitivity and specificity for anti-CCP titre, anti-Sa titre and anti-MCV titre

	Sensitivity, %	Specificity, %	Reference	Total number of patients/controls	Number of RA patients
Anti-CCP	75.4	97.3	[1]	264	118
	66.4	98.3	[2]	237	119
	70.1	98.7	[3]	467	164
	92.8	93.7	[5]	78	56
	72.4	96.1	[6]	479	170
	41	91	[27]a	238	106
	57.9	96	[65]b	373	273
	48	98	[74]c	175	63
Anti-Sa	43	99	[49]	482	206
	31	98	[51]	277	67
	22	98	[27]a	238	106
Anti-MCV	75.6	91.5	[2]	237	119
	69.5	90.8	[3]	467	164
	74.1	79	[6]	479	170
	70.7	95	[65]b	373	273
	54	91	[74]c	175	63
	84	87	[64]	292	92d

^aPatients with recent onset of RA (peripheral joint synovitis of <12 months duration). ^bAt the time of diagnosis [65]. ^cWithin 3 months of the onset of synovitis. ^dSixty-eight RA patients were evaluated to determine anti-MCV sensitivity; 92 RA patients were evaluated to determine anti-MCV specificity.