Table 4.

The top eleven rows of the table are mLRM enthalpy and entropy parameters: E_v, σ_v, E_w and σ_w translated to Lifson-Roid (v,w) and Zimm-Bragg equivalents (σ, s) at T = 300 K. All enthalpies have units of kcal/mol and all entropies are dimensionless “pure” entropies. Free energy differences are calculated by Eq. 6 at T = 300 K. The middle six lines are DCM parameters: δ_a and δ_c are the dimensionless entropy parameters of the alpha helix and coil states (respectively) and v_c is the enthalpy of the coil state. The bottom two lines of the table are average helix propensity from Pace and Scholtz [4] is given by <hp> and their standard deviation given by σ_hp. For GLU and ARG, the Pace and Scholtz values were averaged. Quantities indicated with a dagger superscript are arbitrarily defined to set a reference without loss of generality.

Parameter	Endcap	ALA	Glu/Arg	VAL	GLY
Ev	−0.676	1.06	1.06	1.06	1.06
σv	−3.30	−1.40	−1.40	−1.40	−1.40
Ew	-	−1.09	−0.711	−0.312	−0.09
σw	-	−1.38	−1.38	−1.38	−1.38
v	0.114	0.042	0.042	0.042	0.042
w	-	1.553	0.826	0.424	0.293
σ	0.013	1.77×10−3	1.77×10−3	1.77×10−3	1.77×10−3
s	-	1.395	0.792	0.407	0.294
ΔGLRM	-	−0.264	0.515	0.115	1.736
ΔΔGLRM	-	0	0.78	0.38	2.0
hpLRM	-	0	0.39	0.19	1.0
${\delta }_a^x$	2†	2.60	0.39	1.60	0.39
$v_c^x$	−3.10	−1.27	−0.53	−2.54	−1.43
${\delta }_a^x$	3.50	3.60	3.53	2.40	3.53
ΔGDCM	0.35	−1.045	0.055	−0.725	0.955
ΔΔGDCM	1.85	0	1.10	0.32	2.0
hpDCM	0.93	0	0.32	0.16	1.0
<hp>	-	0	0.6	0.18	1.0
σhp	-	0	0.20	0.22	0