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. Author manuscript; available in PMC: 2012 Apr 1.

Published in final edited form as: Pancreas. 2011 Apr;40(3):453–459. doi: 10.1097/MPA.0b013e31820b9733

A, Tumor volume of subcutaneous MP2^+COX2 and MP2^−COX2 tumors in nude mice. Data are presented as the means ± SD of 5 MP2^+COX2 tumors and of 4 MP2^−COX2 tumors.

B, Immunohistchemistry of COX-2 in representative MP2^+COX2 and MP2^−COX2 tumors.

C, Analysis of COX-2 protein expression in MP2^+COX2 andMP2^−COX2 tumors by Western blot. For positive control (PC), cell lysates of BxPC-3 cells were used. GAPDH expression was used as a loading control.

D, Representative H.E. staining. Left panel, MP2^−COX2 tumors; right panel, MP2^+COX2 tumors. In MP2^−COX2 tumors, there is prominent central necrosis and additional scattered smaller necrotic abscesses with associated neutrophilic inflammation.

A, Tumor volume of subcutaneous MP2^+COX2 and MP2^−COX2 tumors in nude mice. Data are presented as the means ± SD of 5 MP2^+COX2 tumors and of 4 MP2^−COX2 tumors.

B, Immunohistchemistry of COX-2 in representative MP2^+COX2 and MP2^−COX2 tumors.

C, Analysis of COX-2 protein expression in MP2^+COX2 andMP2^−COX2 tumors by Western blot. For positive control (PC), cell lysates of BxPC-3 cells were used. GAPDH expression was used as a loading control.

D, Representative H.E. staining. Left panel, MP2^−COX2 tumors; right panel, MP2^+COX2 tumors. In MP2^−COX2 tumors, there is prominent central necrosis and additional scattered smaller necrotic abscesses with associated neutrophilic inflammation.