Table 2.
Predictors of incident coronary artery disease (CAD) in the full sample and in hepatitis C virus (HCV)–infected and HCV-uninfected groups, by univariable Cox proportional-hazards model.
| Characteristic | Hazard ratio (95% CI) | ||
|---|---|---|---|
| Overall | HCV-infected subjects | HCV-uninfected subjects | |
| HCV infection | 1.01 (0.97–1.05) | … | … |
| Demographic | |||
| Age (5-year increments) | 1.20 (1.19–1.22) | 1.21 (1.19–1.22) | 1.20 (1.18–1.22) |
| Race | |||
| White (comparator) | 1.00 | 1.00 | 1.00 |
| Black | 1.04 (1.00–1.08) | 1.10 (1.04–1.16) | 0.97 (0.92–1.03) |
| Hispanic | 0.78 (0.68–0.89) | 0.63 (0.50–0.78) | 0.90 (0.76–1.06) |
| Other or unknown | 0.73 (0.68–0.78) | 0.60 (0.54–0.66) | 0.87 (0.80–0.95) |
| Female sex | 0.58 (0.50–0.66) | 0.61 (0.50–0.73) | 0.54 (0.45–0.66) |
| Risk factor for CAD | |||
| Hypertension | 1.92 (1.85–1.99) | 2.11 (2.00–2.22) | 1.74 (1.65–1.84) |
| COPD | 1.61 (1.53–1.69) | 1.64 (1.53–1.76) | 1.57 (1.46–1.69) |
| Diabetes | 2.38 (2.29–2.47) | 2.40 (2.28–2.53) | 2.36 (2.23–2.49) |
| Hyperlipidemia | 2.13 (2.04–2.22) | 2.28 (2.17–2.40) | 2.41 (2.23–2.61) |
| Renal failure | 4.70 (4.37–5.05) | 5.01 (4.58–5.48) | 4.14 (3.65–4.70) |
| Other factor | |||
| Anemia | 1.88 (1.79–1.97) | 1.98 (1.86–2.12) | 1.75 (1.63–1.89) |
| Alcohol abuse or dependence | 0.95 (0.91–0.99) | 0.98 (0.93–1.03) | 0.89 (0.83–0.96) |
| Drug abuse or dependence | 0.95 (0.91–0.99) | 0.99 (0.94–1.04) | 0.85 (0.78–0.93) |
NOTE. CI, confidence interval; COPD, chronic obstructive pulmonary disease.