Table 3.
Predictors of incident coronary artery disease (CAD) in the full sample and in hepatitis C virus (HCV)–infected and HCV-uninfected groups, by multivariable Cox proportional-hazards model.
| Characteristic | Hazard ratio (95% CI) | ||
|---|---|---|---|
| Overall | HCV-infected subjects | HCV-uninfected subjects | |
| HCV infection | 1.27 (1.22–1.31) | … | … |
| Demographic | |||
| Age (5-year increments) | 1.14 (1.13–1.16) | 1.14 (1.12–1.15) | 1.15 (1.13–1.17) |
| Race | |||
| White (comparator) | 1.00 | 1.00 | 1.00 |
| Black | 0.89 (0.86–0.93) | 0.90 (0.85–0.95) | 0.89 (0.84–0.94) |
| Hispanic | 0.71 (0.62–0.81) | 0.58 (0.47–0.73) | 0.81 (0.68–0.96) |
| Other or unknown | 0.75 (0.70–0.80) | 0.64 (0.58–0.70) | 0.87 (0.80–0.95) |
| Female sex | 0.70 (0.62–0.81) | 0.72 (0.60–0.86) | 0.69 (0.56–0.84) |
| Risk factor for CAD | |||
| Hypertension | 1.37 (1.32–1.43) | 1.50 (1.42–1.58) | 1.25 (1.18–1.32) |
| COPD | 1.46 (1.39–1.54) | 1.44 (1.34–1.54) | 1.48 (1.38–1.59) |
| Diabetes | 1.82 (1.75–1.90) | 1.79 (1.69–1.89) | 1.87 (1.76–1.98) |
| Hyperlipidemia | 2.08 (2.00–2.18) | 2.06 (1.95–2.17) | 2.14 (1.97–2.31) |
| Renal failure | 2.78 (2.57–3.00) | 2.82 (2.56–3.11) | 2.57 (2.25–2.94) |
| Other factor | |||
| Anemia | 1.37 (1.30–1.44) | 1.42 (1.32–1.53) | 1.32 (1.22–1.43) |
| Alcohol abuse or dependence | 1.04 (0.99–1.09) | 1.06 (0.99–1.13) | 1.01 (0.93–1.10) |
| Drug abuse or dependence | 1.10 (1.04–1.16) | 1.10 (1.03–1.17) | 1.07 (0.96–1.19) |
NOTE. CI, confidence interval; COPD, chronic obstructive pulmonary disease.