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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Hypertension. 2011 Jan 17;57(3):577–585. doi: 10.1161/HYPERTENSIONAHA.110.165274

Figure 1. The AT1A-receptor is deleted from conduit vessels.

Figure 1

(A) Real time PCR performed on aorta stripped of adventitia and endothelium showed that mRNA for the AT1A-receptor was easily detected in aortae from control mice (black bars), but not from SMKOs (white bars)(n ≥ 3, ***P<0.0005 vs. control). AT1A mRNA expression in mesenteric arteries, with intact endothelium and adventitia, was decreased by 60% in SMKO mice compared to controls (n=5,*P<0.05). (B) No difference was seen in AT1B-receptor expression in the aorta between SMKOs and controls (n=3, P=NS).