Figure 4.

Mean nativeness (fraction of native contacts) q_i of each residue i, as a function of the global order parameter Q. Data are averaged over temperatures T = 0.96–1.01. Residues 42–54 and 59–83 in the β-sheet region, which have low contact order [Fig. 2a], retain most of their native contacts even when the rest of the protein is unfolded. This stable core of the protein also contributes to the stability of the α-helix of residues 88–100, due to the large number of contacts between these two domains. Black lines correspond to residues with no native contacts.