Table 1.
Serum Calcium Levels, Serum, FGF-23 Levels and Bone Measurements in Mice
| Group | Ca++* mg/dL ± SEM |
iP mg/dL ± SEM |
FGF23 pg/mL ± SEM |
BMD* Right Femur g/cm2 ± SEM |
BMC* Right Femur g |
BMD* Total g/cm2 ± SEM |
BMC* Total g |
Flexure Stress* mPa |
|---|---|---|---|---|---|---|---|---|
| Sesame Oil | 9.5 ± 0.3 | 7.35 ± 0.36 | 452 ± 93 | 0.0421 ± 0.0016 | 0.0100 ± 0.0006 | 0.0333 ± 0.0011 | 0.188 ± 0.0110 | 51.3167 ± 0.602 |
| 17,20R(OH)2D3 | 9.4 ± 0.3 | 6.77 ± 0.28 | 980 ± 135** | 0.0464 ± 0.0027 | 0.0117 ± 0.0009 | 0.0352 ± 0.0004 | 0.209 ± 0.0120 | 49.8713 ± 0.711 |
| 17,20S(OH)2D3 | 8.9 ± 0.2 | 6.32 ± 0.03 | 634 ± 143 | 0.0450 ± 0.0021 | 0.0110 ± 0.0010 | 0.0342 ± 0.0009 | 0.196 ± 0.0153 | 48.0900 ± 0.836 |
Serum total Ca++ and iP, levels, Bone Mineral Density (BMD) for right femur or total skeleton, Bone Mineral Content (BMC) for right femur or total skeleton, and Flexure Stress in 17,20R(OH)2D3 or 17,20S(OH)2D3 treated mice were not statistically different from sesame oil control treated mice by ANOVA.
P = 0.032 by ANOVA