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. Author manuscript; available in PMC: 2012 Jun 30.
Published in final edited form as: Immunol Lett. 2011 Jan 31;137(1-2):15–27. doi: 10.1016/j.imlet.2011.01.015

Figure 8. Activating mCD36 mAb binds to a novel domain on mouse CD36.

Figure 8

Inhibition of OxLDL induced foam cell formation (A and B) by CD36 peptide was determined as described under ‘methods section’. CD36 peptide was preincubated with activating mCD36 mAb or oxLDL was added to RAW-Blue cells. Supernatant was collected to determine SEAP secretion (C). Effects of CD36 peptide on activating mCD36 mAb or oxLDL binding to RAW-Blue cells were determined by cell ELISA (D). Cells were treated with activating mCD36 mAb (JC63.1) or oxLDL preincubated with CD36- or control peptides were used. Cells treated with DMSO (at 0.2%, vehicle used to dissolve the peptides) were used as an additional control.