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Ingenuity analysis demonstrating significant changes in DNA replication, recombination, and repair pathways in prostatospheres. Genes highlighted in red demonstrate a significant increase in expression in prostatospheres compared to total cells. a LNCaP prostatospheres show an increase in CHK proteins in cell cycle checkpoint control. In PCSC1 (b), PCSC2 (c), and PCSC3 (d), prostatospheres have an increase in genes demonstrating a role of BRCA1 in DNA damage response
