Table 1.
Characteristics of 58 patients with T4a-staged tongue carcinoma
| Characteristic | Primary tumor volume | Total patients | P | |
|---|---|---|---|---|
| <23 ml | ≥23 ml | |||
| No. of patients | 36 | 22 | 58 | |
| Sex, n (%) | ||||
| Female | 4 (11%) | 0 (0%) | 4 (7%) | 0.2868 |
| Male | 32 (89%) | 22 (100%) | 54 (93%) | |
| Age (y) (mean ± SD) | 52.27 ± 12.61 | 48.04 ± 7.65 | 50.67 ± 11.12 | 0.1613 |
| Lymph node, n (%) | ||||
| Negative | 20 (56%) | 7 (32%) | 27 (47%) | 0.0787 |
| Positive | 16 (44%) | 15 (68%) | 31 (53%) | |
| Pathological grade, n (%) | ||||
| Well | 5 (14%) | 3 (14%) | 8 (14%) | 0.8877 |
| Moderate | 29 (80%) | 17 (77%) | 46 (79%) | |
| Poorly | 2 (6%) | 2 (9%) | 4 (7%) | |
| Perineural invasion, n (%) | ||||
| Negative | 19 (53%) | 13 (59%) | 32 (55%) | 0.6390 |
| Positive | 17 (47%) | 9 (41%) | 26 (45%) | |
| Lymphovascular invasion, n (%) | ||||
| Negative | 31 (86%) | 17 (77%) | 48 (55%) | 0.3872 |
| Positive | 5 (14%) | 5 (23%) | 10 (45%) | |
| Cross midline, n (%) | ||||
| Negative | 34 (94%) | 6 (27%) | 40 (69%) | <0.001 |
| Positive | 2 (7%) | 16 (73%) | 18 (31%) | |
| Surgical margin, n (%) | ||||
| Negative | 35 (97%) | 22 (100%) | 57 (98%) | 1.000 |
| Positive | 1 (3%) | 0 (0%) | 1 (2%) | |
| Tumor volume (ml) (mean ± SD) | 12.57 ± 5.56 | 44.14 ± 26.76 | 24.55 ± 2.84 | <0.0001 |
| Follow-up time (mo) (mean ± SD) | 31.30 ± 18.41 | 22.04 ± 14.73 | 27.79 ± 18.45 | 0.0632 |