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. 2011 Mar 14;108(14):5736–5741. doi: 10.1073/pnas.1016358108

Fig. 1.

Fig. 1.

Presence of both KIR2DS3 and IL28B-T synergize to increase the risk of developing chronic HCV infection. ORs for KIR2DS3 alone, IL28B-T carriers (CT or TT) alone, and KIR2DS3 with IL28B-T compared with neither risk factor present were calculated from multinomial logistic regression and used to calculate S and AP. The contribution of individual and combined risk factors to the ORs is graphically represented in the bar chart. Positive OR indicates an association with increased risk for chronic HCV. aOdds ratio (95% confidence interval). bSynergy index (95% confidence interval). cAttributable proportion for interaction (95% confidence interval).