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Histological analyses of 5-week-old mdx and mdxLMα1 muscles. Hematoxylin and eosin staining of quadriceps femoris (Quad), tibialis anterior (TA), gastrocnemius (Gast), triceps brachii (Tri), and diaphragm (Dia) muscles reveals dramatic focal necrosis in both mdx and mdxLMα1 muscles, often covering very large areas of muscle. The TA muscle was least affected by necrosis; only single, small necrotic patches were found. Scale bars: 50 μm.
