A: Box plot. The TOP2A mRNA expression values, measured by gene expression microarrays, according to genomic subtype. B: Box plot. The TOP2A mRNA expression values, measured by Q-PCR, according to genomic subtype. C: Bar chart. The number of TOP2A-positive (POS) and TOP2A-negative (NEG) tumors, according to IHC, for each subtype. D: Bar chart. The number of TOP2A-positive and TOP2A-negative tumors, according to FISH, for each subtype. CNA indicates copy number alteration.